Adenylate Kinase ‹ΖΡWiTakanori Ayabe, ˆ»•”‹M“Tj

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The reaction mechanism of human adenylate kinase.

The steady-state@kinetics of the mutants constructed by protein engineering of site-directed mutagenesis.

 

Takanori Ayabe and Minoru Hamada

Recent Res. Devel. Biochem. 2 (2000): 1-39. Research Signpost. (India)

 

Abstract, FullText, PDF (1-10, 11-20, 21-30, 31-39), and Research Signpost (India), AK Review Figures, Movie Presentation Fig-PDF

 

 

Wiley Encyclopedia of Molecular Medicine, 5 Vol. Set, 2002

Adenylate Kinase

 

Takanori Ayabe and Minoru Hamada,

Edited by Thomas Creighton,

John Wiley & Sons, Inc., New York, NY, pp76-77, 2002.

Wiley Encyclopedia of Molecular Medicine

 

FullText, PDF, and Wiley Encyclopedia (NewYork, USA), Table Contents on WEB

 

 

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Construction of the plasmid pMEX8-hAK1 and random site-directed mutagenesis of human cytosolic adenylate kinase.

 

Takanori Ayabe, Hitoshi Takenaka, Osamu Takenaka, Akiko Takenaka, Hiroyuki Nagahama,Hideharu Maruyama, Atsushi Yamamoto, Masahiko Nagata, Yasunori Koga, Michihiro Sumida, and Minoru Hamada

Biochemistry and Molecular Biology International 38, 373-381, 1996.

 

Abstract (PubMed) and FullText, PDF, Figures & Tables, Movie Presentation, Fig-PDF

 

 

Catalytic roles of Lysines (K9, K27, K31) in the N-terminal domain in human adenylate kinase by random site-directed mutagenesis.

 

Takanori Ayabe, S. K. Park, H. Takenaka, M. Sumida, S. Uesugi, O. Takenaka, and M.Hamada

Biochem. Mol. Biol. Int. 40, 897-906, 1996.

 

Abstract (PubMed) and FullText, PDF, Figures & Tables, Movie Presentation, Fig-PDF

 

 

Steady-state Kinetics of Thr35- and Thr39-mutants in Human Adenylate Kinase by Site-directed Mutagenesis

 

Takanori Ayabe, H. Takenaka, T. Onitsuka, K. Shibata, O. Takenaka, S. Uesugi, and M. Hamada

Enzyme & Protein 49, 305-312, 1996.

 

Abstract (PubMed) and FullText, PDF, Figures & Tables, Movie Presentation, Fig-PDF

 

 

Substrate-Binding and Catalytic Roles of Lys194 In the C-terminus in Human Adenylate Kinase by Site-directed Random Mutagenesis

 

Takanori Ayabe, H. Takenaka, O. Takenaka, T. Onotsuka, K. Shibata, S. Uesugi, and M. Hamada

Biochem. Mol. Biol. Int. 41, 367-375, 1997.

 

Abstract (PubMed) and FullText, PDF, Figures & Tables, Movie Presentation, Fig-PDF

 

Essential Lysine Residues in the N-terminal and the C-terminal Domain of Human Adenylate Kinase Interact with Adenine Nucleotides as found by Site-Directed Random Mutagenesis

 

Takanori Ayabe, H. Takenaka, O. Takenaka, M. Sumida, M. Hideharu, T. Onitsuka, K. Shibata, S. Uesugi, and M. Hamada

Biochemistry 36, 4027-4033, 1997.

 

Abstract (PubMed) and FullText, PDF, Figures & Tables, Movie Presentation, Fig-PDF

 

 

Site-directed mutagenesis and steady-state kinetic analysis of mutant enzymes of human adenylate kinase

 

Takanori Ayabe, Seung Kyu Park, Hiroyuki Nagahama, Hideharu Maruyama, Michihiro Sumida, Hitoshi Takenaka, Osamu Takenaka, Toshio Onitsuka, and Minoru Hamada Biochem.

Mol. Biol. Int. 46, 673-680, 1998.

 

Abstract (PubMed) and FullText, PDF, Figures & Tables, Movie Presentation, Fig-PDF

 

 

Hydrophobic alterations in the C-terminal Domain of Human Adenylate Kinase and the Binding of Adenine Nucleotide Substrates.

 

Takanori Ayabe, Seung Kyu Park, Osamu Takenaka, Hideharu Maruyama, Michihiro Sumida, Toshio Onitsuka, and Minoru Hamada

Journal of Biochemistry 128, 181-187, 2000.

 

Abstract (PubMed) and FullText, (JB on line) , PDF, Figures & Tables, Movie Presentation, Fig-PDF

 

 

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